635 research outputs found

    Cluster algebras from surfaces and extended affine Weyl groups

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    We characterize mutation-finite cluster algebras of rank at least 3 using positive semi-definite quadratic forms. In particular, we associate with every unpunctured bordered surface a positive semi-definite quadratic space V , and with every triangulation a basis in V , such that any mutation of a cluster (i.e., a flip of a triangulation) transforms the corresponding bases into each other by partial reflections. Furthermore, every triangulation gives rise to an extended affine Weyl group of type A, which is invariant under flips. The construction is also extended to exceptional skew-symmetric mutation-finite cluster algebras of types

    CsI(Tl) for WIMP dark matter searches

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    We report a study of CsI(Tl) scintillator to assess its applicability in experiments to search for dark matter particles. Measurements of the mean scintillation pulse shapes due to nuclear and electron recoils have been performed. We find that, as with NaI(Tl), pulse shape analysis can be used to discriminate between electron and nuclear recoils down to 4 keV. However, the discrimination factor is typically (10-15)% better than in NaI(Tl) above 4 keV. The quenching factor for caesium and iodine recoils was measured and found to increase from 11% to ~17% with decreasing recoil energy from 60 to 12 keV. Based on these results, the potential sensitivity of CsI(Tl) to dark matter particles in the form of neutralinos was calculated. We find an improvement over NaI(Tl) for the spin independent WIMP-nucleon interactions up to a factor of 5 assuming comparable electron background levels in the two scintillators.Comment: 16 pages, 8 figures, to be published in Nucl. Instrum. and Meth. in Phys. Res.

    Primary pulmonary cytotoxic T lymphocytes induced by immunization with a vaccinia virus recombinant expressing influenza A virus nucleoprotein peptide do not protect mice against challenge

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    The nucleoprotein (NP) of influenza A virus is the dominant antigen recognized by influenza virus-specific cytotoxic T lymphocytes (CTLs), and adoptive transfer of NP-specific CTLs protects mice from influenza A virus infection. BALB/c mouse cells (H-2d) recognize a single Kd-restricted CTL epitope of NP consisting of amino acids 147 to 155. In the present study, mice were immunized with various vaccinia virus recombinant viruses to examine the effect of the induction of primary pulmonary CTLs on resistance to challenge with influenza A/Puerto Rico/8/34 virus. The minigene ESNP(147-155)-VAC construct, composed of a signal sequence from the adenovirus E3/19K glycoprotein (designated ES) and expressing the 9-amino-acid NP natural determinant (amino acids 147 to 155) preceded by an alanine residue, a similar minigene NP(Met 147-155)-VAC lacking ES, and a full-length NP-VAC recombinant of influenza virus were analyzed. The two minigene NP-VAC recombinants induced a greater primary pulmonary CTL response than the full-length NP-VAC recombinant. However, NP-specific CTLs induced by immunization with ESNP(147-155)-VAC did not decrease peak virus titer or accelerate clearance of virus in the lungs of mice challenged intranasally with A/PR/8/34. Furthermore, NP-specific CTLs induced by immunization did not protect mice challenged intranasally with a lethal dose of A/PR/8/34. Sequence analysis of the NP CTL epitope of A/PR/8/34 challenge virus obtained from lungs after 8 days of replication in ESNP(147-155)-VAC-immunized mice showed identity with that of the input virus, demonstrating that an escape mutant had not emerged during replication in vivo. Thus, in contrast to adoptively transferred CTLs, pulmonary NP-specific CTLs induced by recombinant vaccinia virus immunization do not have protective in vivo antiviral activity against influenza virus infection

    Reservoir Computing Approach to Robust Computation using Unreliable Nanoscale Networks

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    As we approach the physical limits of CMOS technology, advances in materials science and nanotechnology are making available a variety of unconventional computing substrates that can potentially replace top-down-designed silicon-based computing devices. Inherent stochasticity in the fabrication process and nanometer scale of these substrates inevitably lead to design variations, defects, faults, and noise in the resulting devices. A key challenge is how to harness such devices to perform robust computation. We propose reservoir computing as a solution. In reservoir computing, computation takes place by translating the dynamics of an excited medium, called a reservoir, into a desired output. This approach eliminates the need for external control and redundancy, and the programming is done using a closed-form regression problem on the output, which also allows concurrent programming using a single device. Using a theoretical model, we show that both regular and irregular reservoirs are intrinsically robust to structural noise as they perform computation

    Semigroup Closures of Finite Rank Symmetric Inverse Semigroups

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    We introduce the notion of semigroup with a tight ideal series and investigate their closures in semitopological semigroups, particularly inverse semigroups with continuous inversion. As a corollary we show that the symmetric inverse semigroup of finite transformations Iλn\mathscr{I}_\lambda^n of the rank ⩜n\leqslant n is algebraically closed in the class of (semi)topological inverse semigroups with continuous inversion. We also derive related results about the nonexistence of (partial) compactifications of classes of semigroups that we consider.Comment: With the participation of the new coauthor - Jimmie Lawson - the manuscript has been substantially revised and expanded. Accordingly, we have also changed the manuscript titl

    Equivariant geometric K-homology for compact Lie group actions

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    Let G be a compact Lie-group, X a compact G-CW-complex. We define equivariant geometric K-homology groups K^G_*(X), using an obvious equivariant version of the (M,E,f)-picture of Baum-Douglas for K-homology. We define explicit natural transformations to and from equivariant K-homology defined via KK-theory (the "official" equivariant K-homology groups) and show that these are isomorphism.Comment: 25 pages. v2: some mistakes corrected, more detail added, Michael Walter as author added. To appear in Abhandlungen aus dem Mathematischen Seminar der Universit\"at Hambur

    Protecting habitats in low-intensity tropical farmland using carbon-based payments for ecosystem services

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    Tropical land-use change for agricultural expansion is the primary driver of global biodiversity decline. Efforts to stem this decline often focus on protecting pristine habitats or returning farmland to forest, yet such approaches fail to protect vulnerable taxa reliant on habitats within low-intensity farmland. We assess the economic viability of carbon-based payments for ecosystem services (PES) to protect farmland trees and fallowing in Ghana, which provide vital wintering sites for imperiled Afro-palearctic migrant birds and enhance landscape-level carbon storage. We estimate the carbon breakeven prices (BEPs) associated with alternative agricultural management scenarios that protect existing farmland trees. BEPs associated with tree protection on existing farmland were very low, ranging from US2.49toUS2.49 to US6.45 t−1 CO2. Extending and reintroducing fallow periods also carried competitive BEPs, US4.67—US4.67—US15.45 t−1 CO2, when combined with the protection of 50 trees per hectare. Accounting for leakage and economic uncertainty increased BEPs considerably, but scenarios protecting farmland trees and extending fallow periods remained below EU Emissions Trading Scheme prices. Protecting low-intensity farmland habitats and associated biodiversity is cost-effective under carbon-based PES. Implementation should be combined with efforts to close yield gaps, providing greater local food security and resilience

    Comparison of three wet-alkaline methods of digestion of biogenic silica in water

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    Methods for determination of low levels of biogenic silica (0.2–0.4 mg SiO 2 ) in aqueous samples after digestion with three wetalkaline extraction procedures compared favourably in both precision of replicates and recovery of silica utilized by diatoms in budgeted cultures. Leaching samples with 0.2 M NaOH for 10–15 min at 100°C was the least time consuming procedure. Also interference from silicate minerals was lower for this method than leaching with either 0.5 or 5% Na 2 CO 3 for 2 h at 85°C. The use of filters to concentrate samples enables detection of low levels of biogenic silica with colorimetric procedures. Polycarbonate filters are recommended in preference to cellulose acetate or polyvinyl chloride filters for sample collection. Time-course experiments are recommended for establishing digestion times and determining the presence of mineral silicate interference. Wet-alkaline digestion methods are recommended for routine analysis of biogenic silica in suspended matter in preference to infra-red analysis, alkaline fusion and hydrofluoric acid/nitric acid methods.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74725/1/j.1365-2427.1983.tb00658.x.pd
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